Cosmetic composition and preparation of the same



. Haven United States Patent @fice 3,045,199 Patented July 24, 1962 This invention relates to the cosmetic being useful for facial treatments. More particularly, this invention relates to an aerosol cosmetic composition which is useful for cleansing the face and conditioning the skin, said composition comprising an emulsion of active ingredients in the combination with a suitable propellant, and also it relates to the preparation of said composition.

Heretofore almost all the types of cosmetics for facial mask or pack are prepared as powders to be made into a paste or mud with Water, and in the practise, they must be placed in the paste form on the face or the skin for a long period of time, or be applied in combination with massage. Such applications of facial masks are sometimes very troublesome and moreover occasionally induce the contamination of clothes. On the other hand, the composition of the present invention can permit to cause profuse sweating of the face in order to make the pores free from dirt and impurities and to stimulate the local circulation, by such procedures that it comprises covering the face or the skin with the emulsified foam of said composition injected from an aerosol container and, after a short while, removing said foam from the face or the skin.

One object of the present invention is to provide a cosmetic composition which is useful for cleansing the face and conditioning the skin, said composition containing the active ingredients as mentioned hereinafter in the emulsified form together with a suitable propellant. Another object of the present invention is to provide a cosmetic composition useful for facial treatmentsin simpler manner than any conventional cosmetics.

Still another object of the present invention is to provide an oil-in-water type emulsion composition which is free from staining or damaging clothes during usage.

Further object of the present invention is to secure scordinine in the stable state, said scordinine being fairly effective for skin but unstable in the air.

Other objects, features, capabilities and advantages as comprehended by this invention will be apparent from the description and claims which follow.

As well known, scordinine obtained from Allium scorodoprasum L. shows glutathion-like physiological activity and has the function to activate the metabolism for skin. However, the use of this material for cosmetics is quite diflicult because the scordinine readily decomposes or degenerates when contacted with air. I have found a Way to make scordinine stable in cosmetic products. According to the present invention, the composition containing scordinine is filled and sealed together with a suitable propellant in a pressure-resistant container, and it is preserved in aerosol state, whereby the scordinine also can be stable. Also on the application of the cosmetic composition of the present invention, scordinine is not suffered from any change due to interaction with the air, or more precisely, with the humidity in the air, since an air-intercepting effect of the aerosol foam can provide such a period of time that the scordinine in a molecular dispersion state acts on the skin, while the compositoin is app-lied to the face or the skin. In this case adiabatic effect and pleasant stimulus of the persistent foam also promotes blood circulation for the skin, and at the same time these effects together with the wetting-swelling efiect of water in the foam applied serve to adsorption of the active ingredients from the skin.

According to the present invention, a. cosmetic composition being useful for facial treatments, said composition comprising from 0.1% to 0.2% by weight of scordinine and from 0.01% to 0.1% by weight of 4,4,4-trimethyl- 3,3,3 triheptyl-8(2-thiazol)-2,2-pentamethin thiazolocyanin-3,3-diiodide together with from 4% to 12% by weight of a propellant selected from the group consisting of dichlorodifiuoro methane, dichlorotetrafluoro ethane and liquefied petroleum gas, is provided.

The active ingredients of the present invention are scordinine having the presumable structural formula COOH CHNHOGHUOB nu o=o-onrolnon o o-Nn-on-(onin-s-Nn-ii-N-crn N;

coon onicoon 1CI-S and the sensitive dye Platonin-J (NK. 19) 4,4,4-trimethyl-3,3,3-trihepthyl-8- (2"-thiazol) -2,2-pentamethinthiazolocyanin-S,3-diodid having the structural formula The term the sensitive dye used herein indicates the particular sensitive dye as shown above.

The active ingredients are incorporated in an oil-inwater type emulsion which has the prescription as mentioned below. The oil-in-water type emulsion to be incorporated with the active ingredients may contain higher fatty acids such as stearic acid and palmitic acid, lower alkyl esters of higher fatty acid such as isopropyl palmitate and isopropyl myristate, lanolin, liquid paraffin, squalane, non-ionic surface active agent such as polyoxyethylene glycol stearate, stearic monoglyceride, polyoxyethylene sorbitan monostearate and sorbitan monostearate, anionic surface active agent such as sodium stearyl sulfate, and amine such as triethanol amine. The emulsion consisting of about 7 parts by weight of the higher fatty acid, about 4 parts by weight of the nonionic and anionic surface active agents, about 2 parts by weight of the lower alkyl ester of a higher fatty acid, about 1 part by weight of the basic amine and about parts by Weight of water is preferable. In the above prescription, 2 parts by weight of the lower alkyl ester of a higher fatty alcohol may be substituted with 2 parts by weight of lanolin or liquid parafiin. To such an oilin-water type emulsion as described above (its total amount is approximately 114 parts by Weight), about 0.2 part by weight of scordinine and about 0.002 part by weight of the sensitive dye in 10 parts by weight of water are added thereafter. Of course, small amount of perfume may be also added, if desired. The thus prepared emulsified composition, together with a suitable propellant such as dichlorodifluoromethane, dichlorotetrafluoroethane or butane, is immediately filled and sealed into a pressure resistant aerosol container. The relative proportion of the propellant to the emulsified composition may vary depending upon the type of propellant and the type of the emulsion. Generally, the amount of propellant may be Within a range of 3 to 12 parts by weight per 100 parts of the emulsion composition.

In the present invention an aqueous solution of scordinine and the sensitive dye should be mixed with the above mentioned emulsion immediately before filling With the propellant into the aerosol container. The scordinine is relatively stable, when coexisted only with concentrated sensitive dye in an aqueous solution. But the scordinine decomposes or degenerates on standing in the atmosphere in such a concentration of the sensitive dyes that the abovesaid solution is diluted with the emulsion. It is well known that some of sensitive dyes have a physiological effect for human bodies. Also in the present invention it should be noted that the particular sensitive dye used herein is not only essential for keeping scordinine more stable, but also it will show more or less significant physiological activity which is available to human bodies.

In filling the emulsion composition and the propellant into a container an introduction of air should be strictly avoided, otherwise the scordinine of the composition will decompose or degenerate during storage. For this purpose, socalled cold filling, by which the particular amounts of the composition and the propellant gas are mixed and thereafter sealed into a container whereby the air is excluded by the propellant gas, is most preferred. If socalled compressed filling, by which the composition is sealed into a container and then the propellant gas is compressed into the same container, is employed, it is necessary to exclude the air which is originally present in the container with vacuum pump, before filling the composition into the container.

The following examples will serve to illustrate this invention.

Example 1 7g. of stearic acid, 4 g. of polyoxyethylene glycol monostearate, and 2 g. of isopropyl palmitate were heated at about 75 C. and then added with 1 g. of triethanol amine in 100 g. water. The mixture was then stirred vigorously for 1 to 2 minutes and after cooling to room temperature, added with 0.02 cc. of perfume. Thus an oil-in-water type emulsion was prepared.

Then, a solution of 0.2 g. of scordinine and 0.02 g. of the sensitive dye in g. of Water was mixed with the thus prepared emulsion. Immediately thereafter, 100 gr. of the resulting composition were filled together with 8 g. of dichlorodifluoromethane into a pressure resistant aerosol container.

Example 2 The emulsion had the prescription as follows: Stearic acid g 7 Stearyl monoglyceride g 4 Isopropyl myristate g 2 Triethanol amine g 1 Water g 100 Perfume cc 0.02

To the above emulsion, a solution of 0.2 g. of scordinine and 0.02 g. of the sensitive dye in 10 g. water was added. I

100 g. of the thus prepared composition were filled together with 12 g. of dichlorotetrafluoroethane in an aerosol container.

Example 3 The emulsion had the following prescription:

To the above emulsion, a solution of 0.2 g. of scordinine and 0.02 g. of sensitive dye in 10 g. water was added.

100 g. of the thus prepared composition were filled together with 4 g. of butane gas into an aerosol container.

To the above emulsion, a solution of 0.2 g. of scordinine and 0.02 g. of the sensitive dye in 10 g. water was added.

g. of the thus prepared composition were filled together with 3.2 g. of dichloro-difiuoromethane or 6.8 g. of dichlorotetrafluoroethane into a container.

What I claim is:

1. A cosmetic composition being useful for facial treatments, said composition comprising from 0.1% to 0.2% by weight of scordinine and from 0.01% to 0.1% by weight of 4,4,4-trimethyl-3,3,3-triheptyl-8(2-thiazol)-2,2- pentamethin thiazolocyanin-3,3-diiodide together with from 4% to 12% by weight of a propellant selected from the group consisting of dichlorodifluoromethane, dichlorotetrafluoro ethane and liquefied petroleum gas.

2. A cosmetic composition being useful for facial treatments, said composition consisting of 0.1% to 0.2% by weight of scordinine, 0.01% to 0.1% by weight of 4,4, 4-trimethyl-3,3,3-triheptyl-8(2-thiazol) 2,2 pentamethin thiazolocyanine-3,3-diiodid, 4% to 8% by weight of at least one member selected from the group consisting of stearic acid and palmitic acid, 1% to 3% by weight of at least one member selected from the group consisting of isopropyl palmitate, isopropyl myristate, lanolin, liquid paraffin and squalane, 0.7% to 1% by Weight of sodium stearyl sulfate, 2% to 5% by weight of at least one member selected from the group consisting of polyoxyethylene glycol stearate, stearic monoglyceride, polyoxyethylene sorbitan monostearate and sorbitan monostearate, 0.5% to 1.2% by weight of triethanol amine, 4% to 12% by weight of a propellant selected from the group consisting of dichlorodifluoromethane, dichlorotetrafiuoroethane and butane, and the balance of water.

3. A cosmetic composition being useful for facial treatments, said composition consisting of 7 parts by weight of polyoxyethylene glycol monostearate, 2 parts by weight of isopropyl palmitate, 1 part by weight of triethanol amine, 0.2 part by Weight of scordinine, 0.02 part by Weight of 4,4,4-trimethyl-3,3,3-triheptyl-8(2- thiazol)-2,2-pentamethin thiazolocyanine-3,3-diiodide and parts by weight of water together with 10 parts by weight of dichlorofluoromethane.

4. A method for the preparation of a cosmetic composition being useful for facial treatments, which comprises preparing an oil-in-water type emulsion consisting of 7 parts by weight of stearic acid, 4 parts by weight of polyoxyethylene glycol monostearate, 2 parts by weight of isopropyl palmitate, 1 part by weight of triethanol amine and 100 parts by weight of water, mixing the oilin-water type emulsion with an aqueous solution consisting of 0.2 part by weight of scordinine, 0.02 part by weight of 4,4,4-trimethyl-3,3,3-triheptyl-8(2-thiazol)-2,2- pentamethin thiazolocyanine-3,3-diiodide and 10 parts by weight of water and then immediately filling the resulting mixture together with 10 parts by weight of dichlorofluoromethane into an aerosol container.

References Cited in the file of this patent UNITED STATES PATENTS Kendall May 13, 1952 Heseltine Sept. 27, 1955 

2. A COSMETIC COMPOSITION BEING USEFUL FOR FACIAL TREATMENTS, SAID COMPOSITION CONSISTING OF 0.1% TO 0.2% BY WEIGHT OF SCORDININE, 0.01% TO 0.1% BY WEIGHT OF 4,4, 4- TRIMETHYL-3,3,3-TRIHEPTYL-8(2-THIAZOL) -2-2 - PENTAMETHIN THIAZOLOCYANINE-3,3-DIIODID, 4% TO 8% BY WEIGHT OF AT LEAST ONE MEMBER SELECTED FROM THE GROUP CONSISTING OF STEARIC ACID AND PALMITIC ACID, 1% TO 3% BY WEIGHT OF AT LEAST ONE MEMBER SELECTED FROM THE GROUP CONSISTING OF ISOPROPYL PALMITATE, ISOPROPYL MYRISTRATE, LANOLIN, LIQUID PARAFFIN AND SQUALANE, 0.7% TO 1% BY WEIGHT OF SODIUM STEARYL SULFATE, 2% TO 5% BY WEIGHT OF AT LEAST ONE MEMBER SELECTED FROM THE GROUP CONSISTING OF POLYOXYETHYLENE GLYCOL STEARATE, STEARIC MONOGLYCERIDE, POLYOXYETHYLENE SORBITAN MONOSTEARATE AND SORBITAN MONOSTEARATE, 0.5% TO 1.2% BY WEIGHT OF TRIETHANOL, AMINE, 4% TO 12% BY WEIGHT OF A PROPELLANT SELECTED FROM THE GROUP CONSISTING OF DICHLORODIFLUOROMETHANE, DICHLOROTETRAFLUOROETHANE AND BUTANE, AND THE BALANCE OF WATER. 